{"id":3954,"date":"2024-09-23T09:25:52","date_gmt":"2024-09-23T12:25:52","guid":{"rendered":"https:\/\/greenyellow-lyrebird-156652.hostingersite.com\/?p=3954"},"modified":"2024-09-23T09:41:46","modified_gmt":"2024-09-23T12:41:46","slug":"mutacao-do-gene-da-mthfr","status":"publish","type":"post","link":"https:\/\/mundovascular.com.br\/?p=3954","title":{"rendered":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias"},"content":{"rendered":"\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

Muta\u00e7\u00e3o do gene da MTHFR : vou transformar minha vida , agora? <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Primeiramente, voc\u00ea precisa que trombofilia n\u00e3o \u00e9 igual a trombose, e que voc\u00ea pode ter uma vida normal. Respira fundo! Esta tudo bem.<\/span><\/p>

\u00a0<\/p>

A muta\u00e7\u00e3o do gene MTHFR<\/strong> pode impactar a metaboliza\u00e7\u00e3o do \u00e1cido f\u00f3lico e, al\u00e9m disso<\/strong>, afetar os n\u00edveis de homociste\u00edna no sangue. Em outras palavras<\/strong>, essa altera\u00e7\u00e3o gen\u00e9tica influencia o processo de metila\u00e7\u00e3o, o que<\/strong>, por sua vez, pode estar associada a diversos problemas de sa\u00fade.\u00a0\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

Trombofilias e Muta\u00e7\u00e3o do gene da MTHFR<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

No entanto<\/strong>, nem todas as pessoas com a muta\u00e7\u00e3o desenvolvem condi\u00e7\u00f5es graves.<\/span><\/p>

As complica\u00e7\u00f5es desta trombofilia estao mais associadas a problemas de trombose venosa que problemas na arteria.\u00a0<\/p>

Portanto<\/strong>, fatores ambientais e alimentares tamb\u00e9m desempenham um papel importante. Al\u00e9m disso<\/strong>, o acompanhamento m\u00e9dico \u00e9 essencial, j\u00e1 que<\/strong> em muitos casos, suplementos adequados podem ajudar. Por fim<\/strong>, exames gen\u00e9ticos podem detectar a muta\u00e7\u00e3o.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

Hemocisteina alta: o que fazer? <\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Diante disso, a a homociste\u00edna \u00e9 um fator de risco independente para arteriosclerose, acidente vascular cerebral, doen\u00e7a vascular perif\u00e9rica e doen\u00e7a card\u00edaca, por\u00e9m tudo isso \u00e9 MUITO RARO. Entendeu?<\/strong><\/span><\/p>

A muta\u00e7\u00e3o em heterozigose \u00e9 considerada praticamente normal,\u00a0 e homozigose consideramos como doente e devemos ter um cuidado maior nas orienta\u00f5es.\u00a0<\/strong><\/span><\/p>

No entanto, a muta\u00e7\u00e3o C677T s\u00f3 deve ser considerada patog\u00eanica em pacientes homozigotos, pois a heterozigosidade \u00e9 uma variante da normalidade, j\u00e1 que mais de 40% das mulheres brasileiras apresentam essa condi\u00e7\u00e3o.<\/span><\/p>

\u00a0<\/p>

\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

Tive uma TROMBOSE e descobri a trombofilia? <\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Tive uma trombose venosa profunda (TVP) ou embolia pulmonar (EP), e meu m\u00e9dico fez exames e descobriu que meus n\u00edveis de homociste\u00edna est\u00e3o elevados. Devo tomar \u00e1cido f\u00f3lico, vitamina B6 e B12 ou uma combina\u00e7\u00e3o das tr\u00eas?”<\/span><\/p>

N\u00e3o.<\/strong> Embora o uso desses suplementos reduza os n\u00edveis de homociste\u00edna, isso n\u00e3o significa<\/strong> que ele diminua o risco de novos co\u00e1gulos. Ou seja<\/strong>, mesmo que os n\u00edveis de homociste\u00edna sejam controlados, n\u00e3o h\u00e1 evid\u00eancias<\/strong> de que isso previna recorr\u00eancias. Por isso<\/strong>, \u00e9 importante seguir as orienta\u00e7\u00f5es do m\u00e9dico, j\u00e1 que<\/strong> outros tratamentos podem ser mais eficazes.<\/span><\/p>

A trombofilia pode ocorrer por problema heredit\u00e1rio ou por condi\u00e7\u00f5es adquiridas como: c\u00e2ncer, gravidez, obesidade, uso de medicamentos, como anticoncepcionais orais, entre outros.<\/span>
<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t

Preciso de um tratamento especial para Muta\u00e7\u00e3o do gene da MTHFR? <\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

N\u00e3o. O paciente com TVP, EP, doen\u00e7a cardiovascular ou complica\u00e7\u00f5es na gravidez, que foi testado para muta\u00e7\u00f5es no gene MTHFR sem respaldo nas diretrizes profissionais e baseadas em evid\u00eancias, e que apresentou uma ou duas muta\u00e7\u00f5es, deve ser tratado da mesma forma que aqueles sem essas muta\u00e7\u00f5es. A presen\u00e7a de muta\u00e7\u00f5es no gene MTHFR n\u00e3o exige tratamento especial, exceto suplementa\u00e7\u00e3o com \u00e1cido f\u00f3lico, vitamina B6 ou B12, e n\u00e3o traz preocupa\u00e7\u00f5es adicionais em alguns casos.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t
AGENDAMENTO DE CONSULTAS EM SP, Fortaleza ou Online CLIQUE AQUI<\/span><\/span><\/strong><\/em><\/a><\/h6>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Muta\u00e7\u00e3o do gene da MTHFR : vou transformar minha vida , agora? Primeiramente, voc\u00ea precisa que trombofilia n\u00e3o \u00e9 igual a trombose, e que voc\u00ea pode ter uma vida normal. Respira fundo! Esta tudo bem. \u00a0 A muta\u00e7\u00e3o do gene MTHFR pode impactar a metaboliza\u00e7\u00e3o do \u00e1cido f\u00f3lico e, al\u00e9m disso, afetar os n\u00edveis de … <\/p>\n

Continue reading “Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias”<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_joinchat":[],"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3954","post","type-post","status-publish","format-standard","hentry","category-sem-categoria"],"yoast_head":"\nMuta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu<\/title>\n<meta name=\"description\" content=\"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mundovascular.com.br\/?p=3954\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu\" \/>\n<meta property=\"og:description\" content=\"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mundovascular.com.br\/?p=3954\" \/>\n<meta property=\"og:site_name\" content=\"Dr. \u00cdtalo Abreu\" \/>\n<meta property=\"article:published_time\" content=\"2024-09-23T12:25:52+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-09-23T12:41:46+00:00\" \/>\n<meta name=\"author\" content=\"mundovascular\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"mundovascular\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954\"},\"author\":{\"name\":\"mundovascular\",\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#\\\/schema\\\/person\\\/8cadb04535e5c02d9bb55063e53fef5e\"},\"headline\":\"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias\",\"datePublished\":\"2024-09-23T12:25:52+00:00\",\"dateModified\":\"2024-09-23T12:41:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954\"},\"wordCount\":525,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#\\\/schema\\\/person\\\/8cadb04535e5c02d9bb55063e53fef5e\"},\"articleSection\":[\"Sem categoria\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954\",\"url\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954\",\"name\":\"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#website\"},\"datePublished\":\"2024-09-23T12:25:52+00:00\",\"dateModified\":\"2024-09-23T12:41:46+00:00\",\"description\":\"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/?p=3954#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/mundovascular.com.br\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#website\",\"url\":\"https:\\\/\\\/mundovascular.com.br\\\/\",\"name\":\"Dr. \u00cdtalo Abreu\",\"description\":\"M\u00e9dico Crirugi\u00e3o Vascular\",\"publisher\":{\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#\\\/schema\\\/person\\\/8cadb04535e5c02d9bb55063e53fef5e\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/mundovascular.com.br\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":[\"Person\",\"Organization\"],\"@id\":\"https:\\\/\\\/mundovascular.com.br\\\/#\\\/schema\\\/person\\\/8cadb04535e5c02d9bb55063e53fef5e\",\"name\":\"mundovascular\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/greenyellow-lyrebird-156652.hostingersite.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/italoLOGO.-ATUAL.png\",\"url\":\"https:\\\/\\\/greenyellow-lyrebird-156652.hostingersite.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/italoLOGO.-ATUAL.png\",\"contentUrl\":\"https:\\\/\\\/greenyellow-lyrebird-156652.hostingersite.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/italoLOGO.-ATUAL.png\",\"width\":842,\"height\":595,\"caption\":\"mundovascular\"},\"logo\":{\"@id\":\"https:\\\/\\\/greenyellow-lyrebird-156652.hostingersite.com\\\/wp-content\\\/uploads\\\/2021\\\/06\\\/italoLOGO.-ATUAL.png\"},\"sameAs\":[\"https:\\\/\\\/greenyellow-lyrebird-156652.hostingersite.com\"],\"url\":\"https:\\\/\\\/mundovascular.com.br\\\/?author=1\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu","description":"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mundovascular.com.br\/?p=3954","og_locale":"en_US","og_type":"article","og_title":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu","og_description":"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.","og_url":"https:\/\/mundovascular.com.br\/?p=3954","og_site_name":"Dr. \u00cdtalo Abreu","article_published_time":"2024-09-23T12:25:52+00:00","article_modified_time":"2024-09-23T12:41:46+00:00","author":"mundovascular","twitter_card":"summary_large_image","twitter_misc":{"Written by":"mundovascular","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/mundovascular.com.br\/?p=3954#article","isPartOf":{"@id":"https:\/\/mundovascular.com.br\/?p=3954"},"author":{"name":"mundovascular","@id":"https:\/\/mundovascular.com.br\/#\/schema\/person\/8cadb04535e5c02d9bb55063e53fef5e"},"headline":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias","datePublished":"2024-09-23T12:25:52+00:00","dateModified":"2024-09-23T12:41:46+00:00","mainEntityOfPage":{"@id":"https:\/\/mundovascular.com.br\/?p=3954"},"wordCount":525,"commentCount":0,"publisher":{"@id":"https:\/\/mundovascular.com.br\/#\/schema\/person\/8cadb04535e5c02d9bb55063e53fef5e"},"articleSection":["Sem categoria"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/mundovascular.com.br\/?p=3954#respond"]}]},{"@type":"WebPage","@id":"https:\/\/mundovascular.com.br\/?p=3954","url":"https:\/\/mundovascular.com.br\/?p=3954","name":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias - Dr. \u00cdtalo Abreu","isPartOf":{"@id":"https:\/\/mundovascular.com.br\/#website"},"datePublished":"2024-09-23T12:25:52+00:00","dateModified":"2024-09-23T12:41:46+00:00","description":"Muta\u00e7\u00e3o do gene da MTHFR e trombofilias, tenho risco de trombose? Quando devo fazer exames? Saiba todos os pontos importantes desse tema.","breadcrumb":{"@id":"https:\/\/mundovascular.com.br\/?p=3954#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mundovascular.com.br\/?p=3954"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mundovascular.com.br\/?p=3954#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mundovascular.com.br\/"},{"@type":"ListItem","position":2,"name":"Muta\u00e7\u00e3o do gene da MTHFR e Trombofilias"}]},{"@type":"WebSite","@id":"https:\/\/mundovascular.com.br\/#website","url":"https:\/\/mundovascular.com.br\/","name":"Dr. \u00cdtalo Abreu","description":"M\u00e9dico Crirugi\u00e3o Vascular","publisher":{"@id":"https:\/\/mundovascular.com.br\/#\/schema\/person\/8cadb04535e5c02d9bb55063e53fef5e"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mundovascular.com.br\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":["Person","Organization"],"@id":"https:\/\/mundovascular.com.br\/#\/schema\/person\/8cadb04535e5c02d9bb55063e53fef5e","name":"mundovascular","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/greenyellow-lyrebird-156652.hostingersite.com\/wp-content\/uploads\/2021\/06\/italoLOGO.-ATUAL.png","url":"https:\/\/greenyellow-lyrebird-156652.hostingersite.com\/wp-content\/uploads\/2021\/06\/italoLOGO.-ATUAL.png","contentUrl":"https:\/\/greenyellow-lyrebird-156652.hostingersite.com\/wp-content\/uploads\/2021\/06\/italoLOGO.-ATUAL.png","width":842,"height":595,"caption":"mundovascular"},"logo":{"@id":"https:\/\/greenyellow-lyrebird-156652.hostingersite.com\/wp-content\/uploads\/2021\/06\/italoLOGO.-ATUAL.png"},"sameAs":["https:\/\/greenyellow-lyrebird-156652.hostingersite.com"],"url":"https:\/\/mundovascular.com.br\/?author=1"}]}},"_links":{"self":[{"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/posts\/3954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3954"}],"version-history":[{"count":34,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/posts\/3954\/revisions"}],"predecessor-version":[{"id":3991,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=\/wp\/v2\/posts\/3954\/revisions\/3991"}],"wp:attachment":[{"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mundovascular.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}